(1-Diazo-2-oxopropyl)-phosphonic Acid Dimethyl Ester

[90965-06-3] C5H9N2O4P (MW 192.11) InChI = 1S/C5H9N2O4P/c1-4(8)5(7-6)12(9,10-2)11-3/h1-3H3 InChIKey = SQHSJJGGWYIFCD-UHFFFAOYSA-N (reagent used for the conversion of aldehydes into terminal alkynes). Alternate Name: dimethy(1-diazo-2-oxopropyl) phosphonate. Solubility: H2O (no data); alcohols (MeOH); chloroalkanes (CHCl3). Form Supplied in: colorless to yellow liquid; one supplier (Digital Specialty Chemicals Ltd.). Analysis of Reagent Purity: IR, NMR (CDCl3). Purification: flash column chromatography (silica-gel, PE–EtOAc, 1:1). Handling, Storage, and Precautions: air and moisture stable but incompatible with oxidizing agents. Wear safety goggles, protecting clothing, and gloves. Handle in an efficient fume hood. Store in a cool, dry place in a tightly sealed container. Maybe harmful by inhalation, ingestion, or skin absorption. May cause eye irritation, may cause skin irritation. To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. In case of contact, immediately flush eyes with copious amounts of water for at least 15 min. In case of contact, immediately wash skin with soap and copious amounts of water. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, wash out mouth with water provided person is conscious. Call a physician. Wash contaminated clothing before reuse.