磷酸戊糖途径
内分泌学
二羟丙酮
酮体
磷酸二羟丙酮
内科学
分解代谢
过度换气
新陈代谢
丙酮酸
化学
糖酵解
医学
生物化学
甘油
磷酸盐
作者
Kye-Wing Chow,Wilson G. Pond,E. F. Walker
标识
DOI:10.3181/00379727-134-34742
摘要
The chronological events occurring in blood after intoxicating doses of ammonium carbonate were studied using the suckling pig. Physical manifestations included vomiting, hyperventilation, hypersensitivity to sound, convulsions, and tetany followed by death in some cases. Blood glucose, dihydroxyacetone-P, pyruvate and lactate were raised indicating failure to decarboxylate pyruvate. Elevated blood ketone bodies indicated increased fat catabolism as a result. Consistent rise in blood pentose may either be due to an inhibition of the pentose phosphate pathway or an increased metabolism of glucose via this pathway to make up for reducing power lost through impairment of the TCA cycle.
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