动能
体积热力学
核磁共振
磁导率
常量(计算机编程)
示踪剂
反应速率常数
体积流量
血浆体积
磁共振成像
化学
核医学
动力学
分析化学(期刊)
物理
热力学
计算机科学
色谱法
核物理学
医学
膜
程序设计语言
内分泌学
量子力学
生物化学
放射科
作者
Paul S. Tofts,Gunnar Brix,David L. Buckley,Jeffrey L. Evelhoch,Elizabeth Henderson,Michael V. Knopp,Henrik Larsson,Ting-Yim Lee,Nina A. Mayr,Geoff J.M. Parker,Ruediger E. Port,June S. Taylor,Robert M. Weisskoff
标识
DOI:10.1002/(sici)1522-2586(199909)10:3<223::aid-jmri2>3.0.co;2-s
摘要
We describe a standard set of quantity names and symbols related to the estimation of kinetic parameters from dynamic contrast-enhanced T(1)-weighted magnetic resonance imaging data, using diffusable agents such as gadopentetate dimeglumine (Gd-DTPA). These include a) the volume transfer constant K(trans) (min(-1)); b) the volume of extravascular extracellular space (EES) per unit volume of tissue v(e) (0 < v(e) < 1); and c) the flux rate constant between EES and plasma k(ep) (min(-1)). The rate constant is the ratio of the transfer constant to the EES (k(ep) = K(trans)/v(e)). Under flow-limited conditions K(trans) equals the blood plasma flow per unit volume of tissue; under permeability-limited conditions K(trans) equals the permeability surface area product per unit volume of tissue. We relate these quantities to previously published work from our groups; our future publications will refer to these standardized terms, and we propose that these be adopted as international standards.
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