医学
银屑病
皮肤病科
特应性皮炎
免疫学
自分泌信号
旁分泌信号
蕈样真菌病
淋巴瘤
不利影响
白细胞介素
细胞因子
受体
内科学
作者
Danah M Holman,Amer N. Kalaaji
出处
期刊:PubMed
日期:2006-06-01
卷期号:5 (6): 520-4
被引量:16
摘要
Cytokines are polypeptides that are produced by various cell types and act in an autocrine or paracrine manner. They have many different biological actions and have been used in dermatology to treat a wide range of dermatologic diseases. In this paper we review some of the more commonly used cytokines in dermatology, including interferon-alpha and -gamma, interleukins-2 and -10, and granulocyte-macrophage colony-stimulating factor. We specifically examine their roles in the treatment of condyloma and verruca, hemangiomas, keloids, skin cancers, atopic dermatitis, psoriasis, Behcet disease, chronic granulomatous disease, wound healing, and cutaneous T cell lymphoma. In addition, some of the adverse effects associated with these cytokines are discussed.
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