An Unexpected Domino Reaction of β‐Keto Sulfones with Acetylene Ketones Promoted by Base: Facile Synthesis of 3(2H)‐Furanones and Sulfonylbenzenes

Abstract An unexpected domino reaction of β‐keto sulfones with acetylene ketones has been developed. The domino reaction of β‐keto sulfones with diynones proceeded smoothly in the presence of 30 mol% K 2 CO 3 without other additives, and afforded the novel 3(2 H )‐furanone derivatives. On replacing the diynones with terminal alkyne ketones, the reaction regioselectivity was changed and sulfonylbenzenes were obtained via benzannulation in good yields. magnified image