托珠单抗
医学
Graves眼病
甲状腺
耐火材料(行星科学)
格雷夫斯病
眼病
内科学
胃肠病学
外科
疾病
天体生物学
物理
作者
Aileen Sy,Kasra Eliasieh,Rona Z. Silkiss
出处
期刊:Ophthalmic Plastic and Reconstructive Surgery
[Ovid Technologies (Wolters Kluwer)]
日期:2016-06-10
卷期号:33 (3): e55-e57
被引量:41
标识
DOI:10.1097/iop.0000000000000730
摘要
Tocilizumab, in a preliminary study, was reported to be an effective therapy for moderate to severe thyroid eye disease. The authors describe the clinical response of 2 severe thyroid eye disease cases refractory to intravenous steroids and orbital decompression. Both patients demonstrated improved clinical activity scores with minimal side effects after tocilizumab therapy. In addition, post tocilizumab orbital fat biopsies demonstrated benign adipose tissue without evidence of inflammatory cells.
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