Flow-Cytometric Analysis of Mouse Platelet Function

Characterization of platelet-membrane glycoproteins and their intracellular signaling pathways has become essential to understanding platelet function not only in the context of thrombosis and hemostasis, but also other processes like inflammation, tumor metastasis, and atherosclerosis. Besides their central role in these processes in vivo, platelets are increasingly used as a convenient and physiologically relevant model for basic studies on cell adhesion and signaling processes.