The dataset contains the raw data of the figures and tables reported in the open access publication “M. Zeppilli, B. Matturro, E. Dell’Armi, L. Cristiani, M.P. Papini, S. Rossetti, M. Majone, Reductive/oxidative sequential bioelectrochemical process for Perchloroethylene (PCE) removal: effect of the applied reductive potential and microbial community characterization, Journal of Environmental Chemical Engineering (2020) 104657.