NK, JL report no financial relationships with commercial interests. Dr. Singh has received grant support from the Mayo Clinic, the National Network of Depression Centers, Breakthrough Discoveries for Thriving with Bipolar Disorder and the National Institutes of Health. Dr. Singh is a KL2 Mentored Career Development Program scholar, supported by CTSA grant number KL2TR002379 from the National Center for Advancing Translational Science (NCATS). Dr. Singh has received honoraria (to institution) from Elsevier for editing a Clinical Overview on Treatment-Resistant Depression. All authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The data that support the findings of this study are available from the corresponding author upon reasonable request.