EtOH-mediated cascade C(sp3)‒H alkylation via aromatization-driven [1,6]-hydride transfer: green and divergent synthesis of spirocyclic azepino[4,3,2-cd]indoles

The development of green and efficient methods for construction of azepinoindole skeletons remains highly desirable yet challenging. Described herein is the EtOH-mediated cascade C(sp3)‒H alkylation reactions of 4-dialkylamino-indole-3-carbaldehydes for green...