克隆形成试验
造血
癌细胞
癌症研究
体外
生物
癌症
免疫学
细胞生物学
干细胞
遗传学
作者
Miriam Pons,Mandy Beyer
标识
DOI:10.1007/978-1-0716-2788-4_2
摘要
One of the main characteristics of cancer is the rapid proliferation of transformed cells. Cancer therapies aim to kill such cells. Cancer clones surviving therapy can be resistant to the treatment, but they can also lose the ability to proliferate. The ability of single cells to proliferate can be monitored in vitro and can provide insights into the sensitivity of tumor cells to chemotherapeutics. The following chapter describes how clonogenic hematopoietic cell growth can be determined with the colony formation assay.
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