At present, information technology has been widely used in the daily lives of people, and social media has changed their daily living habits. In this context, the rapid development of we-media has become a hot issue in the current society, which brings new opportunities and challenges for corporate brand communication in the new era. Nowadays, people’s consumption habits have changed from the traditional offline to the combination of online and offline. In this regard, enterprises should constantly explore and innovate the concept and method of we-media brand communication. This paper will start from the importance of enterprise we-media brand communication, and analyze the characteristics and effective strategies of enterprise we-media brand communication in the new era.