吉非替尼
医学
腺癌
肺腺癌
进行性疾病
内科学
基因检测
肿瘤科
突变
阶段(地层学)
罕见病
抗药性
表皮生长因子受体
疾病
病理
癌症
基因
生物
遗传学
古生物学
作者
Guixian Wu,Qian Chen,Dongqing Lv,Ling Lin,Jing Huang
出处
期刊:Recent Patents on Anti-cancer Drug Discovery
[Bentham Science]
日期:2023-03-17
卷期号:19 (2): 247-252
标识
DOI:10.2174/1574892818666230316145232
摘要
Although epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have been proven a long-lasting treatment effect in pulmonary adenocarcinoma, most patients still progressed within one year due to the acquired resistance. Complex mutations of rare rare sites after acquiring resistance are rarely reported in pulmonary adenocarcinoma.
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