Thromboelastography in Long-Term Antiplatelet Therapy for Patients Diagnosed with Benign Prostate Hyperplasia Undergoing Holmium Laser Enucleation of the Prostate: A Retrospective Study

医学 剜除术 前列腺 泌尿科 良性前列腺增生(BPH) 增生 回顾性队列研究 血栓弹性成像 前列腺切除术 外科 内科学 血小板 癌症
作者
Zhi-Bo Gu,Lei Qiu,Hua Zhu,Ming‐De Lu,Jiangang Chen
出处
期刊:Therapeutics and Clinical Risk Management [Dove Medical Press]
卷期号:Volume 20: 633-639
标识
DOI:10.2147/tcrm.s472153
摘要

Objective: To compare low-vs high-power HoLEP effects on coagulation in patients on antiplatelet (AP) therapy via thromboelastography (TEG).Methods: 210 patients was retrospectively analyzed and stratificated into three discrete groups, specifically: Group A (AP therapy, high-power HoLEP, n = 72); Group B (AP therapy, low-power HoLEP, n=73); Group C (no AP therapy, low-power HoLEP, n = 65).Baseline characteristics and coagulation profiles via TEG were compared.Univariate and multivariate analyses were conducted to identify independent risk factors associated with hematuria.Furthermore, parameters such as IPSS, Qmax, post-void residual volume V 2 and PSA levels were recorded during 1year follow-up.Results: No differences in terms of baseline characteristics across all groups.Significant differences were observed in the duration of enucleation, morcellation, bladder irrigation, post-operative catheterization, length of hospital stay and the extent of hemoglobin reduction (F = 54.06,8.54, 6.68, 9.24, 17.06, 5.97, p < 0.05).No differences were noted in postoperative hematuria, urine retention, transfusion rates, and SUI (x 1 2 = 1.082 ; x 2 2 = 0.197,; x 3 2 = 3.981;x 4 2 = 0.816, p > 0.05).Univariate and multivariate analyses revealed that prostate volume emerged as an independent risk factor for hematuria (OR 1.080, 95% CI: 1.007-1.158,p = 0.031).Clinical outcomes including Qmax, IPSS, V 2 , and PSA demonstrated significant enhancement during 1 year follow-up. Conclusion:Compared to HP-HoLEP, LP-HoLEP effectively reduces surgical and subsequent processing times, decreases hospital stay duration, and diminishes hemoglobin decline, offering a viable option without discontinuing AP therapy.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Eureka完成签到 ,获得积分10
1秒前
2秒前
蔚蔚蓝天完成签到,获得积分10
2秒前
追寻依风完成签到,获得积分10
2秒前
2秒前
ddsyg126完成签到,获得积分10
2秒前
有魅力的从凝完成签到,获得积分10
2秒前
史呆芬发布了新的文献求助10
2秒前
欣慰的白羊完成签到,获得积分10
3秒前
3秒前
4秒前
煎饼煎饼完成签到,获得积分10
4秒前
淡然觅荷完成签到 ,获得积分10
4秒前
jack1511完成签到,获得积分10
4秒前
庄怀逸完成签到 ,获得积分10
5秒前
单薄的大白菜真实的钥匙完成签到,获得积分10
6秒前
八荒来犬发布了新的文献求助10
6秒前
无私雪碧发布了新的文献求助10
7秒前
呆萌黑猫完成签到,获得积分10
7秒前
8秒前
8秒前
归尘发布了新的文献求助20
8秒前
李泽完成签到,获得积分10
9秒前
冷艳的白莲完成签到,获得积分10
9秒前
风信子完成签到,获得积分10
9秒前
斯文败类应助啊啊啊啊采纳,获得10
9秒前
amberzyc应助阿巴阿巴采纳,获得10
10秒前
ChengYonghui完成签到,获得积分10
11秒前
飞雪完成签到,获得积分10
11秒前
12秒前
12秒前
liutg24完成签到,获得积分10
12秒前
dd发布了新的文献求助10
12秒前
精明尔曼完成签到,获得积分10
12秒前
13秒前
yirenli完成签到,获得积分10
13秒前
13秒前
hesongwen完成签到,获得积分10
14秒前
刘英丽发布了新的文献求助10
14秒前
逐暮完成签到,获得积分20
14秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
A new approach to the extrapolation of accelerated life test data 1000
徐淮辽南地区新元古代叠层石及生物地层 500
Coking simulation aids on-stream time 450
北师大毕业论文 基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 390
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
Robot-supported joining of reinforcement textiles with one-sided sewing heads 360
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4015970
求助须知:如何正确求助?哪些是违规求助? 3555964
关于积分的说明 11319479
捐赠科研通 3289040
什么是DOI,文献DOI怎么找? 1812373
邀请新用户注册赠送积分活动 887882
科研通“疑难数据库(出版商)”最低求助积分说明 812044