Amide Proton Transfer Weighted MR Imaging for Predicting Meningioma Stiffness: A Feasibility Study

磁共振成像 脑膜瘤 刚度 核医学 医学 质子 材料科学 核磁共振 放射科 物理 核物理学 复合材料
作者
Hao Yu,Laimin Zhu,Yanting Wang,Xiuzheng Yue,Weiwei Wang,Zhanguo Sun,Shanshan Jiang,Yue‐Qin Chen,Zhibo Wen
出处
期刊:Journal of Magnetic Resonance Imaging [Wiley]
卷期号:57 (4): 1071-1078
标识
DOI:10.1002/jmri.28379
摘要

Stiffness of meningioma is an important factor affecting the surgical resection and the prognosis of patients.To examine the feasibility of APTw-magnetic resonance imaging (MRI) in evaluating meningioma stiffness.Retrospective.Seventy-one patient with meningiomas, 39 were male and 32 were female; the mean age was 51 ± 10 years.3.0T; Turbo-spin-echo T1 -weighted and Gd-T1 -weighted sequence; Turbo-spin-echo T2 -weighted sequence; 2D fat-suppressed, turbo-spin-echo APTw pulse sequence.The T1 WI signal intensity score, T2 WI signal intensity score, APTwmin , APTwmax , and APTwmean values were compared between soft, medium stiff and stiff meningiomas or non-stiff meningiomas and stiff meningiomas group.Chi-square test, one-way ANOVA analysis, independent-samples t-test, intra-class correlation coefficient, rank-sum test, receiver operating characteristic curve analysis. P < 0.05 was considered statistically significant in all tests.APTwmin and APTwmean in the stiff group were significantly lower than that in the non-stiff group (2.79% ± 0.42% vs. 1.90% ± 0.60% and 3.20% ± 0.31% vs. 2.55% ± 0.61%). APTwmin and APTwmean in the stiff group were significantly lower than that in the medium stiff and soft groups (1.90% ± 0.60% vs. 2.69% ± 0.40% and 3.12% ± 0.32%, 2.55% ± 0.61% vs. 3.17% ± 0.33% and 3.39% ± 0.18%), APTwmin in the medium stiff group was significantly lower than in the soft group, there was no significant difference in APTwmean between the medium stiff and soft groups (P = 0.190). APTwmin showed the best diagnostic performance for evaluating meningioma stiffness with an area under the curve of 0.913, when the APTwmin was lower than 2.4%, the meningioma was defined as a stiff tumor, the sensitivity, specificity, and accuracy were 87.1%, 87.5%, and 85.9%, respectively.APTw-MRI could be used to evaluate meningioma stiffness, with APTwmin having the best evaluative efficiency.3 TECHNICAL EFFICACY: Stage 1.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
薛珊珊完成签到,获得积分10
刚刚
淘金者1314发布了新的文献求助10
1秒前
2秒前
Porifera完成签到,获得积分10
2秒前
笨鸟先飞发布了新的文献求助10
2秒前
科研小助完成签到,获得积分10
3秒前
星辰大海应助gggwj采纳,获得10
4秒前
领导范儿应助竹竿采纳,获得10
4秒前
5秒前
pursuingx完成签到,获得积分20
5秒前
MG_aichy完成签到,获得积分10
5秒前
Titi完成签到 ,获得积分10
5秒前
6秒前
Yifan2024完成签到,获得积分0
7秒前
zz完成签到,获得积分10
7秒前
wanwei完成签到,获得积分10
8秒前
洛洛发布了新的文献求助10
9秒前
科研小助发布了新的文献求助10
10秒前
hhh完成签到 ,获得积分10
10秒前
细腻依云发布了新的文献求助20
11秒前
小马甲应助笨鸟先飞采纳,获得10
11秒前
画风湖湘卷完成签到,获得积分10
12秒前
XLH发布了新的文献求助10
12秒前
14秒前
15秒前
Lucas应助长孙归尘采纳,获得10
15秒前
项之桃完成签到,获得积分10
15秒前
香菜完成签到,获得积分10
15秒前
Xiaoxin_Ju完成签到,获得积分10
16秒前
愤怒也哈哈完成签到,获得积分10
16秒前
lc完成签到,获得积分10
16秒前
疗伤烧肉粽完成签到,获得积分10
16秒前
17秒前
mhl11应助勤恳的饭饭采纳,获得10
17秒前
小马甲应助lhcshuang采纳,获得10
17秒前
mtl115完成签到 ,获得积分10
17秒前
Liu完成签到 ,获得积分10
19秒前
Meya发布了新的文献求助10
19秒前
ew.完成签到,获得积分10
21秒前
22秒前
高分求助中
Production Logging: Theoretical and Interpretive Elements 2000
Very-high-order BVD Schemes Using β-variable THINC Method 1200
RNAの科学 ―時代を拓く生体分子― 金井 昭夫(編) 1000
BIOLOGY OF NON-CHORDATES 1000
进口的时尚——14世纪东方丝绸与意大利艺术 Imported Fashion:Oriental Silks and Italian Arts in the 14th Century 800
Autoregulatory progressive resistance exercise: linear versus a velocity-based flexible model 550
Education and Upward Social Mobility in China: Imagining Positive Sociology with Bourdieu 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 细胞生物学 免疫学 冶金
热门帖子
关注 科研通微信公众号,转发送积分 3353809
求助须知:如何正确求助?哪些是违规求助? 2978293
关于积分的说明 8685108
捐赠科研通 2659822
什么是DOI,文献DOI怎么找? 1456369
科研通“疑难数据库(出版商)”最低求助积分说明 674342
邀请新用户注册赠送积分活动 665110