肾病
免疫学
遗传倾向
发病机制
内科学
医学
半乳糖
内分泌学
生物
糖尿病
疾病
生物化学
作者
Yan‐na Wang,Shu‐Feng Zhou,Pei‐Jer Chen,Guizhen Yu,Xue Zhang,Ping Hou,Lijun Liu,Sufang Shi,Jicheng Lv,Hong Zhang
出处
期刊:Journal of The American Society of Nephrology
日期:2021-02-16
卷期号:32 (3): 545-552
被引量:40
标识
DOI:10.1681/asn.2020060823
摘要
Our data identify GALNT12 as a novel gene associated with galactose-deficient IgA1 and suggest novel genetic interactions. These findings support a key role of genetically conferred dysregulation of galactose-deficient IgA1 in the development of IgA nephropathy.
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