染色质
癌症研究
生物
癌症
遗传学
突变
计算生物学
DNA
基因
作者
Dane Vassiliadis,Mark A. Dawson
出处
期刊:Nature
[Nature Portfolio]
日期:2021-02-03
卷期号:590 (7847): 557-558
被引量:2
标识
DOI:10.1038/d41586-021-00211-y
摘要
Cancer-associated mutations promote the formation of pancreatic tumours after tissue injury, but how this occurs is unclear. Changes to chromatin in injured cells with such mutations explain this predisposition to malignancy. How Kras mutations aid the formation of pancreatic tumours.
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