共轭体系
细胞内
纳米技术
细菌
细胞外
材料科学
聚合物
化学
生物
生物化学
遗传学
复合材料
作者
Chunlei Zhu,Qiong Yang,Fengting Lv,Libing Liu,Shu Wang
标识
DOI:10.1002/adma.201204550
摘要
Multifunctional cationic conjugated polyelectrolyte (CP)-coated bacteria are fabricated for drug loading, delivery and release with multimodal anticancer activity. Facilitated by the collaborative release effect caused by CP and an antibiotic polymyxin B, the loaded toxins leak out from the vectors in considerable amounts and lead to tumor cell death. In addition, the CP coated bacterial vectors can sentisize ROS, which favors light-mediated tumor cell killing. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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