医学
结直肠癌
淋巴
对比度(视觉)
动态对比度
动态增强MRI
放射科
磁共振成像
核医学
癌症
病理
内科学
计算机科学
人工智能
作者
Xinyue Yang,Yan Chen,Wen Zhang,Baolan Lu,Bingqi Shen,Xiaojuan Xiao,Shenping Yu
出处
期刊:American Journal of Roentgenology
[American Roentgen Ray Society]
日期:2019-01-01
卷期号:212 (1): 77-83
被引量:15
摘要
The aim of this study was to discriminate metastatic from nonmetastatic regional lymph nodes (LNs) with short-axis diameters of less than 5 mm in rectal cancer using quantitative parameters derived from dynamic contrast-enhanced (DCE) MRI.Sixty-five LNs from 122 patients were evaluated, including malignant LNs (n = 27) and benign LNs (n = 38). The following parameters were assessed: the forward volume transfer constant (Ktrans), reverse volume transfer constant (kep), fractional extravascular extracellular space volume (Ve), short-axis diameter, long-axis diameter, and short- to long-axis diameter ratio. ROC curves were used to analyze statistically significant parameters.Metastatic LNs exhibited a lower Ktrans than did nonmetastatic LNs (p < 0.001), but the other parameters were not significantly different between the two groups. The AUC of the Ktrans was 0.732, with a 95% CI of 0.610-0.854, and the diagnostic cutoff value was 0.088 min-1 (sensitivity, 60.5%; specificity, 81.5%).Ktrans had moderate diagnostic performance in assessing small regional LNs in rectal cancer and appears to be a useful predictor when distinguishing malignant LNs from benign LNs only by morphology is difficult.
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