Copper‐Catalyzed Asymmetric Ring‐Opening of Cyclic Diaryliodonium with Benzylic and Aliphatic Amines

Abstract A Cu‐catalyzed asymmetric ring‐opening reaction between cyclic diaryliodonium and benzylic or aliphatic amines has been developed. At low concentration of the amines, realized by either mixing the amines with Lewis acid or slow addition of the amines, the reaction afforded the products in high enantioselectivity. magnified image