Recent advances in microfluidic-aided chitosan-based multifunctional materials for biomedical applications

纳米技术 微流控 壳聚糖 材料科学 药物输送 工程类 化学工程
作者
Yang Gao,Qingming Ma,Jie Cao,Yiwen Wang,Xin Yang,Qiulong Xu,Qing Liang,Yong Sun
出处
期刊:International Journal of Pharmaceutics [Elsevier]
卷期号:600: 120465-120465 被引量:36
标识
DOI:10.1016/j.ijpharm.2021.120465
摘要

Chitosan-based biomaterials has shown great advantages in a broad range of applications, including drug delivery, clinical diagnosis, cell culture and tissue engineering. However, due to the lack of control over the fabrication processes by conventional techniques, the wide application of chitosan-based biomaterials has been hampered. Recently, microfluidics has been demonstrated as one of the most promising platforms to fabricate high-performance chitosan-based multifunctional materials with monodisperse size distribution and accurately controlled morphology and microstructures, which show great promising for biomedical applications. Here, we review recent progress of the fabrication of chitosan-based biomaterials with different structures and integrated functions by microfluidic technology. A comprehensive and in-depth depiction of critical microfluidic formation mechanism and process of various chitosan-based materials are first interpreted, with particular descriptions about the microfluidic-mediated control over the morphology and microstructures. Afterwards, recently emerging representative applications of chitosan-based multifunctional materials in various fields, are systematically summarized. Finally, the conclusions and perspectives on further advancing the microfluidic-aided chitosan-based multifunctional materials toward potential and versatile development for fundamental researches and biomedicine are proposed.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
赘婿应助cheersyu采纳,获得10
1秒前
222222完成签到,获得积分20
1秒前
专一的代丝完成签到,获得积分10
1秒前
Accept2024发布了新的文献求助10
1秒前
西红柿完成签到,获得积分10
2秒前
3秒前
4秒前
传奇3应助科研通管家采纳,获得10
4秒前
科研通AI5应助科研通管家采纳,获得10
4秒前
Ava应助科研通管家采纳,获得10
4秒前
充电宝应助科研通管家采纳,获得10
4秒前
徐之易发布了新的文献求助10
4秒前
香蕉觅云应助科研通管家采纳,获得10
4秒前
一一应助科研通管家采纳,获得100
4秒前
情怀应助科研通管家采纳,获得10
4秒前
优雅的羊青完成签到,获得积分10
4秒前
斯文败类应助科研通管家采纳,获得10
4秒前
思源应助科研通管家采纳,获得10
4秒前
李爱国应助科研通管家采纳,获得10
4秒前
852应助科研通管家采纳,获得10
4秒前
5秒前
安紊完成签到,获得积分10
5秒前
kkc完成签到,获得积分10
5秒前
6秒前
迟大猫应助LL采纳,获得10
6秒前
张张发布了新的文献求助20
7秒前
甜甜圈完成签到,获得积分20
7秒前
中森明菜完成签到,获得积分20
7秒前
文毛完成签到,获得积分10
7秒前
A123456完成签到,获得积分10
7秒前
小马甲应助失望采纳,获得10
8秒前
8秒前
慕青应助huhu采纳,获得10
8秒前
舒适白凡发布了新的文献求助10
9秒前
如意元霜发布了新的文献求助10
9秒前
诚心凌文完成签到,获得积分10
9秒前
9秒前
Forever完成签到,获得积分10
10秒前
10秒前
QA完成签到,获得积分10
10秒前
高分求助中
Production Logging: Theoretical and Interpretive Elements 2700
Mechanistic Modeling of Gas-Liquid Two-Phase Flow in Pipes 2500
Kelsen’s Legacy: Legal Normativity, International Law and Democracy 1000
Handbook on Inequality and Social Capital 800
Conference Record, IAS Annual Meeting 1977 610
Interest Rate Modeling. Volume 3: Products and Risk Management 600
Interest Rate Modeling. Volume 2: Term Structure Models 600
热门求助领域 (近24小时)
化学 材料科学 生物 医学 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 量子力学 光电子学 冶金
热门帖子
关注 科研通微信公众号,转发送积分 3546815
求助须知:如何正确求助?哪些是违规求助? 3123829
关于积分的说明 9357111
捐赠科研通 2822447
什么是DOI,文献DOI怎么找? 1551477
邀请新用户注册赠送积分活动 723475
科研通“疑难数据库(出版商)”最低求助积分说明 713766