Circulating Thyroid-Stimulating Hormone Receptor Messenger Rna as a Marker of Tumor Aggressiveness in Patients with Papillary Thyroid Microcarcinoma

Background: We have previously shown that thyroid-stimulating hormone receptor messenger RNA (TSHR mRNA) is detectable in the peripheral blood of patients with papillary thyroid microcarcinoma (PTmC). The aim of this study was to analyze the utility of TSHR mRNA status as a marker of tumor aggressiveness in patients with PTmC.