Application of response surface method in the separation of radioactive material: a review

Abstract Response Surface Method (RSM) is one of the most popular and powerful tools for experimental design and optimization. This paper first reviewed the research progress of RSM in the separation and recovery of various radioactive materials, and verified the application of RSM in adsorption isotherm analysis and thermodynamic calculation. The main advantage of RSM in radioactive material separation is the reduction in the number of experiments required, resulting in considerably less radioactive material consumption, secondary waste generation, workload and radiation dose, which is valuable for the research of radioactive material separation.