The structure of Crimean-Congo hemorrhagic fever virus Gc is revealed; many more still need an answer

• The structure of glycoprotein Gc, responsible for membrane fusion, is revealed, but many more mysteries remain. • Why do only antibodies against Gc have neutralizing effect, but not the one against Gn? • Why can NAbs against Gc only be protective in the animals in preventive settings, but not in the therapeutic administration?