脂质体
卵磷脂
磷脂
化学
色谱法
磷脂酰胆碱
磷脂酰胆碱
蛋黄卵磷脂
维生素E
维生素
膜
生物化学
抗氧化剂
作者
Ivana Arsić,Gordana Vuleta
标识
DOI:10.1046/j.1467-2494.1999.181682.x
摘要
Lecithin has an antioxidative potential that depends directly on the content of phospholipids. Purified lecithin with a higher phospholipid content exerts better antioxidative properties. Furthermore, due to its specific physico‐chemical properties, amphiphility in particular, the phospholipid the largest portion of the lecithin lipids, forms enclosed membrane systems (liposomes) in the presence of water. Liposomes encapsulate hydro and liposoluble, pharmacologically and cosmetically active components. The relatively poor stability of vitamin A considerably limits its use in topical preparations. Protection against an oxidation process is the main reason for vitamin A encapsulation in the liposomes made from the purified phospholipid fraction (90% phosphatidyl choline). It increases the vitamin A‐palmitate stability against the oxidation process caused by UV radiation. Lecithin used for preparing the liposomes increases vitamin A stability during UV radiation in pure liposome dispersion or liposomes with vitamin A incorporated in polyacrylate gel as a vehicle.
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