Comparative Properties and Methods of Preparation of Lipid Vesicles (Liposomes)

IAbbreviations used in this article are as follows: AraC= l -,B-d arabinofuranosyl cytosine, Chol=cholesterol, DNA=deoxyribonucleic acid, DMPA=dimyristoyl phos­ phatidic acid, DMPC = dimyristoyl phosphatidylcholine, DMPE = dimyristoyl phos­ phatidylethanolamine, DOPC = dioleoyl phosphatidylcholine, DOPE = dioleoyl phos­ phatidylethanolamine, DPPA=dipaJmitoyl phosphatidic acid, DPPC=dipaJmitoyl phos­ phatidylcholine, DPPG = dipaJmitoyl phosphatidylglycerol, DPPS;= dipalmitoyl phos­ phatidylserine, DSPC = distearoyl phosphatidylcholine, EPC = egg phosphatidylcholine, EDTA=ethylene diamine tetracetic acid, HDL=high density lipoprotein, HPLC=high performance liquid chromatography, LUV = large unilamellar vesicle, MLV = multilamellar vesicle, NT A = nitrilotriacetic acid, NMR = nuclear magnetic resonance, PA phosphatidic acid, PC = phosphatidylcholine, PE = phosphatidylethanolamine, PO = phosphatidylglycerol, PS = phosphatidylserine, REV = reverse-phase evaporation vesicle, RNA = ribonucleic acid, SUV=small unilameUar vesicle, Tc=transition temperature. 2Present address: Department of Physiology, Tufts University School of Medicine, Boston, Massachusetts 02111.