Recent Innovative Strategies for the Synthesis of Amines: From CN Bond Formation to CN Bond Activation

Reconsider the use of amines: A new trend for the synthesis of different amine derivatives is presented by using the inherent reactivity of an existing CN bond of simpler amines. Typical amination methods are based on the addition of the NH bond enabled through the nucleophilicity of the amine. Novel reactions using amines as reagent also concentrate on the use of the mentioned CN bond to activate the α-carbon atom as reacting part of the amine.