The lower He-sea points playing a significant role in postoperative ileus in colorectal cancer treated with acupuncture: based on machine-learning

医学 足三里 针灸科 电针 肠梗阻 结直肠癌 排便 随机对照试验 不利影响 内科学 外科 癌症 替代医学 病理
作者
Xu Zhang,Wenjing Yang,Junliang Shang,Wenchao Dan,Lin Shi,Tong Li,Guowang Yang
出处
期刊:Frontiers in Oncology [Frontiers Media SA]
卷期号:13
标识
DOI:10.3389/fonc.2023.1206196
摘要

Postoperative ileus (POI) is a common complication following abdominal surgery, which can lead to significant negative impacts on patients' well-being and healthcare costs. However, the efficacy of current treatments is not satisfactory. The purpose of this study was to evaluate the therapeutic effects of acupuncture intervention and explore the regulation of acupoint selection for treating POI in colorectal cancer (CRC) patients.We searched eight electronic databases to identify randomized controlled trials (RCTs) on acupuncture for POI in CRC and conducted a meta-analysis. Subsequently, we utilized the Apriori algorithm and the Frequent pattern growth algorithm, in conjunction with complex network and cluster analysis, to identify association rules of acupoints.The meta-analysis showed that acupuncture led to significant reductions in time to first defecation (MD=-20.93, 95%CI: -25.35, -16.51; I2 = 93.0%; p < 0.01; n=2805), first flatus (MD=-15.08, 95%CI: -18.39, -11.76; I2 = 96%; p < 0.01; n=3284), and bowel sounds recovery (MD=-10.96, 95%CI: -14.20, -7.72; I2 = 94%; p < 0.01; n=2043). A subgroup analysis revealed that acupuncture not only reduced the duration of POI when administered alongside conventional care but also further expedited the recovery of gut function after colorectal surgery when integrated into the enhanced recovery after surgery (ERAS) pathway. The studies included in the analysis reported no instances of serious adverse events associated with acupuncture. We identified Zusanli (ST36), Shangjuxu (ST37), Neiguan (PC6), Sanyinjiao (SP6), Xiajuxu (ST39), Hegu (LI4), Tianshu (ST25), and Zhongwan (RN12) as primary acupoints for treating POI. Association rule mining suggested potential acupoint combinations including {ST37, ST39}≥{ST36}, {PC6, ST37}≥{ST36}, {SP6, ST37}≥{ST36}, and {ST25, ST37}≥{ST36}.Meta-analysis indicates acupuncture's safety and superior effectiveness over postoperative care alone in facilitating gastrointestinal recovery. Machine-learning approaches highlight the importance of the lower He-sea points, including Zusanli (ST36) and Shangjuxu (ST37), in treating POI in CRC patients. Incorporating additional acupoints such as Neiguan (PC6) (for pain and vomiting) and Sanyinjiao (SP6) (for abdominal distension and poor appetite) can optimize treatment outcomes. These findings offer valuable insights for refining treatment protocols in both clinical and experimental settings, ultimately enhancing patient care.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
成就的斑马完成签到,获得积分10
1秒前
内含子发布了新的文献求助10
1秒前
2秒前
不胜玖发布了新的文献求助10
3秒前
领导范儿应助shan采纳,获得10
3秒前
Joany完成签到,获得积分10
3秒前
经竺应助xzy998采纳,获得10
4秒前
十一完成签到 ,获得积分10
6秒前
赘婿应助九月秋采纳,获得10
6秒前
nini发布了新的文献求助10
7秒前
烧饼发布了新的文献求助10
7秒前
传奇3应助苹果善若采纳,获得10
8秒前
账户已注销应助lxb采纳,获得30
8秒前
彼岸花完成签到 ,获得积分10
8秒前
9秒前
所所应助科研通管家采纳,获得10
10秒前
我是老大应助科研通管家采纳,获得10
10秒前
李健的小迷弟应助啵啵采纳,获得30
10秒前
科研通AI2S应助科研通管家采纳,获得10
10秒前
天天快乐应助科研通管家采纳,获得10
10秒前
于芋菊应助科研通管家采纳,获得10
10秒前
科研通AI2S应助科研通管家采纳,获得10
10秒前
思源应助科研通管家采纳,获得10
10秒前
于芋菊应助科研通管家采纳,获得10
10秒前
orixero应助科研通管家采纳,获得10
10秒前
天天快乐应助科研通管家采纳,获得10
10秒前
于芋菊应助科研通管家采纳,获得10
10秒前
10秒前
11秒前
11秒前
上官若男应助科研通管家采纳,获得10
11秒前
11秒前
月月完成签到,获得积分10
12秒前
13秒前
14秒前
pass发布了新的文献求助10
14秒前
keke完成签到,获得积分10
14秒前
16秒前
薰硝壤应助hongshao0504采纳,获得10
16秒前
16秒前
高分求助中
Impact of Mitophagy-Related Genes on the Diagnosis and Development of Esophageal Squamous Cell Carcinoma via Single-Cell RNA-seq Analysis and Machine Learning Algorithms 2000
Evolution 1100
How to Create Beauty: De Lairesse on the Theory and Practice of Making Art 1000
Gerard de Lairesse : an artist between stage and studio 670
CLSI EP47 Evaluation of Reagent Carryover Effects on Test Results, 1st Edition 550
T/CAB 0344-2024 重组人源化胶原蛋白内毒素去除方法 500
[Procedures for improving absorption properties of polystyrene microtest plates by coating with nitrocellulose] 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 2983573
求助须知:如何正确求助?哪些是违规求助? 2644688
关于积分的说明 7139617
捐赠科研通 2277924
什么是DOI,文献DOI怎么找? 1208526
版权声明 592164
科研通“疑难数据库(出版商)”最低求助积分说明 590427