Design of membrane-based microfluidic chip device based on bionic leaf and adsorption detection of tetracycline antibiotics by specific gel membrane

In this study, we developed copper alginate-carbon nanotube/copper sulfide-graphene oxide gel membranes based on the design inspired by the surface structure of leaves and plant transpiration in nature and through the modulation of high-density polymer networks. This light-driven water evaporation-specific adsorption gel membrane is capable of using solar energy to drive water evaporation from contaminated surface water to access tetracycline antibiotics for detection. Combined with the designed biomimetic adsorption detection chip, in situ monitoring of tetracycline antibiotics in water bodies was achieved. Compared with the traditional mass spectrometry detection method, it shows more outstanding performance in terms of time, environmental protection and technology. The microscale adsorption mechanism was further explored on the molecular scale by density functional theory (DFT). The results showed that tetracycline antibiotics were adsorbed on the aerogel membrane mainly through π-πEDA interactions in sandwich (S) configuration and parallel displacement (PD) configuration, which ensured high adsorption efficiency. Under the optimized conditions, the tetracycline concentration detected by the sensor showed a good linear relationship with the cyclic voltammetry curve, and the lowest detection limit was 1.59*10−4 μM. This adsorption detection strategy can reduce the influence of organic matter, inorganic matter, and other classes of antibiotics on the detection of tetracycline antibiotics, and provide a new idea for the high-efficiency photo-thermal actuation and in-situ testing of tetracycline antibiotics.