免疫分析
医学
疾病
重症监护医学
心理干预
生物标志物
可靠性(半导体)
病理
免疫学
生物
精神科
物理
生物化学
功率(物理)
量子力学
抗体
作者
Fernándo González‐Ortiz,Thomas K. Karikari,Kaj Blennow
摘要
Abstract Alzheimer's disease (AD) represents a growing global health challenge, necessitating accurate and reliable diagnostic methodologies for timely intervention and management. Immunoassays, specifically designed to detect biomarkers associated with AD pathology, have emerged as pivotal tools in diagnostic development. Understanding of the established protocols ensures assay sensitivity, specificity, and reproducibility, thereby enhancing the clinical utility of these diagnostic tools. Here, we explore the considerations in immunoassay development, focusing on phosphorylated tau217 assays. Ultimately, a clear understanding of immunoassay development is paramount in advancing the precision and reliability of AD diagnostics, contributing to early detection, improved patient outcomes, and advancements in therapeutic interventions.
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