Regulatory mechanism of cysteine-dependent methionine biosynthesis in Bifidobacterium longum : insights into sulfur metabolism in gut microbiota

Sulfur, a critical element for bacterial growth, is not directly utilized by bifidobacteria, rendering the sulfur-containing amino acid biosynthesis pathway, particularly for cysteine and methionine, poorly understood. This research identifies six genes involved in this pathway through re-annotation of the