Agreement Between Two Optical Biometers Based on Large Coherence Length SS-OCT and Scheimpflug Imaging/Partial Coherence Interferometry

PURPOSE: To evaluate the agreement between measurements obtained with a new optical biometer (Argos; Movu Inc) using large coherence length swept-source optical coherence tomography (SS-OCT) and those obtained with an optical biometer with a rotating Scheimpflug camera, combined with partial coherence interferometry (PCI) (Pentacam AXL; Oculus Optikgeräte GmbH) in adults. METHODS: The following measurements were examined and evaluated: axial length, central corneal thickness (CCT), anterior chamber depth (ACD), mean keratometry, J 0 and J 45 vectors, and corneal diameter. Measurements with the two biometers were conducted in triplicate per instrument in a random order by the same examiner. Paired t tests were employed to compare the difference between the two devices. The Bland-Altman method was implemented to assess their agreement. RESULTS: A total of 145 patients were enrolled in the study. The differences between the Scheimpflug/PCI–based biometer and the SS-OCT biometer were as follows: −0.02 ± 0.05 mm for axial length, 1.15 ± 5.79 µm for CCT, −0.04 ± 0.04 mm for ACD, −0.28 ± 0.16 diopters (D) for mean keratometry, 0.01 ± 0.11 D for J 0 , −0.02 ± 0.10 D for J 45 , and −1.03 ± 0.62 mm for corneal diameter. Bland-Altman plots showed narrow ranges in axial length, CCT, ACD, mean keratometry, and J 0 and J 45 , which implied excellent agreement between the two biometers. Corneal diameter displayed poor agreement, with a 95% limits of agreement ranging from −2.25 to 0.19 mm. CONCLUSIONS: Excellent agreement was established between the measurements provided by the new optical biometer based on SS-OCT and the optical biometer using Scheimpflug imaging and PCI, except for corneal diameter. [ J Refract Surg . 2020;36(7):459–465.]