医学
哮喘
安慰剂
随机化
置信区间
内科学
苯拉唑马布
嗜酸性粒细胞
临床终点
随机对照试验
美波利祖马布
病理
替代医学
作者
Andrew Menzies‐Gow,Jonathan Corren,Arnaud Bourdin,Geoffrey Chupp,Elliot Israel,Michael E. Wechsler,Christopher Brightling,José-Marie Griffiths,Åsa Hellqvist,Karin Bowen,Primal Kaur,Gun Almqvist,Sandhia Ponnarambil,Gene Colice
标识
DOI：10.1056/nejmoa2034975
摘要
Tezepelumab is a human monoclonal antibody that blocks thymic stromal lymphopoietin, an epithelial-cell–derived cytokine implicated in the pathogenesis of asthma. The efficacy and safety of tezepelumab in patients with severe, uncontrolled asthma require further assessment.
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