Electrocatalytic Oxidation of Thiols on a TEMPO Modified Electrode

Abstract Monothiols were oxidized efficiently and quantitatively to disulfides on graphite felt electrode coated with 4-amino-2,2,6,6-tetramethylpiperidinyl-1-oxyl (4-amino-TEMPO). The 4-amino-TEMPO was immobilized through an amide linkage with poly(acrylic acid). The poly(acrylic acid) was cross-linked with 1,6-diaminohexane, and the residual carboxyl groups were methylated with diazomethane. The electrode was stable and could be used repeatedly.