Palladium-Catalysed Direct Arylation using Free-Amine-Substituted Polyfluoroanilines with Inhibition of Amination-Type Reaction

Abstract The palladium‐catalysed C−C bond formation via direct arylation of free‐amine‐substituted polyfluoroaniline derivatives proceeds in moderate to high yields with a variety of aryl bromides. The nature of the base was found to be crucial to promote the direct arylation with inhibition of the amination reaction.