Of Mice and MAVS–Diabetic Kidney Disease and the Leaky Gut

Kidney physiology and the gut microbiome are intricately linked. The kidneys remotely sense changes in microbial metabolism.[1][1] In advanced CKD, retained microbial metabolites contribute to the syndrome of uremia.[2][2] Experimental models of CKD exhibit changes in the gut microbiome[3][3] and