Synthesis of Si‐Stereogenic Silanols by Catalytic Asymmetric Hydrolytic Oxidation

Despite growing progress in the construction of chiral organosilicon compounds, the catalytic asymmetric synthesis of silicon-stereogenic silanols is less explored and remains a considerable challenge. Herein, we report the first enantioselective construction of silicon-stereogenic silanols by the catalytic asymmetric hydrolytic oxidation of dihydrosilanes. This practical procedure features ambient reaction conditions, high atom economy, good functional-group compatibility, and H2 as the only by-product, and produces a wide range of valuable chiral silanols and bis-silanols in decent yields with excellent chemo- and stereoselectivity.