Hypothalamus

前脑 连合 地板 生物 基底前脑 大脑 解剖 外侧下丘脑 下丘脑 神经板 前连合 神经科学 神经管 中枢神经系统 胚胎 细胞生物学
作者
Luis Puelles,Margaret Martínez‐de‐la‐Torre,Sylvia M. Bardet,John L. R. Rubenstein
出处
期刊:Elsevier eBooks [Elsevier]
卷期号:: 221-312 被引量:95
标识
DOI:10.1016/b978-0-12-369497-3.10008-1
摘要

Neuroanatomical concepts of the hypothalamus, the forebrain territory that controls homeostasis and drives in vertebrates, are over 100 years old. Neuroanatomists of the 19th century generally considered the hypothalamus to consist of the tuberal or infundibular area, a median prominence at the brain ventral surface at the location of the pituitary gland, framed in front and at the sides by the optic chiasm and tracts. The neural plate fate maps of amniotes and anamniotes are strictly comparable from a topological point of view. The relative positions of the prospective brain areas can be extrapolated from one species to another. The prospective longitudinal or axial dimension of the brain is best represented by the neural/non-neural border of the neural plate, which will transform into the longitudinal roof plate of the closed neural tube. This developmental analysis suggests that all adult median forebrain derivatives found between the anterior commissure and the mamillary area are equally rostralmost loci in the brain. At the open neural plate, the rostral forebrain primordium contains the prospective hypothalamus as a large area centered upon the alar, basal, and floor portions of the terminal wall, its caudal part covering as well a rostral part of the lateral wall, whereas the prospective telencephalon forms a thin band at the dorsal periphery of the alar portion of these domains, including the corresponding roof area. A handful of genes, coding either for transcription factors or secreted protein morphogens, participate in early patterning and regional identity specification along the AP and DV dimensions of the whole forebrain, including the hypothalamus. The complex networked interplay of many molecular signals that control brain development represents a dynamic ontogenetic system that tends to reach different equilibrium states in different parts of the neuroepithelial wall.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
xiaoxiaojiang发布了新的文献求助10
1秒前
wanci应助1112采纳,获得10
2秒前
shi完成签到,获得积分10
2秒前
好运莲莲完成签到,获得积分10
2秒前
钱邦国发布了新的文献求助200
3秒前
18238496540完成签到,获得积分10
3秒前
3秒前
量子星尘发布了新的文献求助10
4秒前
5秒前
7秒前
李爱国应助机灵的茹妖采纳,获得10
8秒前
科研狗完成签到,获得积分10
9秒前
9秒前
9秒前
幸符发布了新的文献求助10
9秒前
有魅力哈密瓜完成签到,获得积分10
10秒前
英俊的铭应助xiaoxiaojiang采纳,获得10
10秒前
幸运花花完成签到,获得积分10
10秒前
共享精神应助研究僧采纳,获得10
12秒前
12秒前
诚心的尔阳完成签到,获得积分10
12秒前
韩涵发布了新的文献求助10
13秒前
KKKpumc完成签到,获得积分10
14秒前
思源应助科研通管家采纳,获得10
14秒前
15秒前
15秒前
领导范儿应助科研通管家采纳,获得10
15秒前
yx_cheng应助科研通管家采纳,获得50
15秒前
15秒前
科研通AI2S应助科研通管家采纳,获得10
15秒前
今后应助科研通管家采纳,获得10
15秒前
科研通AI5应助科研通管家采纳,获得10
15秒前
15秒前
15秒前
15秒前
15秒前
慕青应助科研通管家采纳,获得10
15秒前
YGJ发布了新的文献求助10
16秒前
夕夕口口发布了新的文献求助10
16秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Effective Learning and Mental Wellbeing 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3975953
求助须知:如何正确求助?哪些是违规求助? 3520269
关于积分的说明 11201866
捐赠科研通 3256738
什么是DOI,文献DOI怎么找? 1798436
邀请新用户注册赠送积分活动 877578
科研通“疑难数据库(出版商)”最低求助积分说明 806464