后代
肥胖
生理学
医学
体育锻炼
干预(咨询)
糖尿病
2型糖尿病
怀孕
内分泌学
内科学
生物
遗传学
精神科
作者
Johan E. Harris,Lisa A. Baer,Kristin I. Stanford
标识
DOI:10.1016/j.tem.2018.01.003
摘要
Maternal exercise improves metabolic health in adult male and female offspring. Maternal exercise negates the detrimental effects of an impaired maternal diet on the metabolic health of the offspring. Maternal exercise before and during pregnancy is necessary to confer maximal beneficial effects to offspring. The intrauterine environment can modulate the course of development and confer an enduring effect on offspring health. The effects of maternal diet to impair offspring metabolic health are well established, but the effects of maternal exercise on offspring metabolic health have been less defined. Because physical exercise is a treatment for obesity and type 2 diabetes (T2D), maternal exercise is an appealing intervention to positively influence the intrauterine environment and improve the metabolic health of offspring. Recent research has provided insights into the effects of maternal exercise on the metabolic health of adult offspring, which is the focus of this review. The intrauterine environment can modulate the course of development and confer an enduring effect on offspring health. The effects of maternal diet to impair offspring metabolic health are well established, but the effects of maternal exercise on offspring metabolic health have been less defined. Because physical exercise is a treatment for obesity and type 2 diabetes (T2D), maternal exercise is an appealing intervention to positively influence the intrauterine environment and improve the metabolic health of offspring. Recent research has provided insights into the effects of maternal exercise on the metabolic health of adult offspring, which is the focus of this review.
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