WCN24-1671 THE METABOLIC VULNERABILITY INDEX, REFLECTING MALNUTRITION AND INFLAMMATION, PREDICTS MORTALITY IN KIDNEY TRANSPLANT RECIPIENTS

Both malnutrition and inflammation affect patient outcome after kidney transplantation. The Metabolic Vulnerability Index (MVX) is a novel multi-marker risk score encompassing 6 metabolic malnutrition biomarkers, i.e. the glycoprotein inflammation biomarker, GlycA, small HDL, branched chain amino acids (valine, leucine and isoleucine), and the mitochondrial dysfunction biomarker, citrate. The utility of this biomarker risk score has not been determined in solid organ transplantation cohorts. We aimed to evaluate the prognostic value of MVX in kidney transplant recipients (KTRs).