KHMDS Mediated Ring-Opening/Reconstruction of Anthranils with Arylacetonitriles: Synthesis of Multisubstituted 2-Aminoquinoline N-Oxides

A convenient and atom-economical protocol for the construction of multisubstituted 2-aminoquinoline N -oxides using readily available starting materials anthranil and arylacetonitrile has been reported. The KHMDS mediated process tolerates various protecting...