嘌呤能受体
嘌呤能信号
P2Y受体
生物
细胞生物学
受体
细胞外
P2受体
G蛋白偶联受体
肠上皮
信号转导
兴奋剂
腺苷受体
生物化学
上皮
遗传学
作者
Kristen A. Engevik,Francesca J. Scribano,J. Thomas Gebert,Jacob L. Perry,Sue E. Crawford,Joseph M. Hyser
出处
期刊:American Journal of Physiology-gastrointestinal and Liver Physiology
[American Physiological Society]
日期:2024-02-01
卷期号:326 (2): G107-G119
被引量:1
标识
DOI:10.1152/ajpgi.00108.2023
摘要
Several studies have revealed crucial roles for P2 receptors during inflammatory and infectious diseases, however, these have largely been demonstrated in immune cells and the enteric nervous system. Although epithelial cells serve as the first barrier against infection and inflammation, the role of purinergic signaling within the gastrointestinal tract remains largely unknown. This work expands our knowledge of purinergic receptor distribution and relative expression along the intestine.
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