Brachial Plexopathy After Single-Fraction Stereotactic Body Radiation Therapy in Apical Lung Tumors

医学 不良事件通用术语标准 臂丛神经病变 臂丛神经 放射治疗 放射科 队列 核医学 外科 内科学
作者
Austin J. Iovoli,Sharan Prasad,H Malhotra,Nadia Malik,Simon Fung-Kee-Fung,Anurag K. Singh,Mark Farrugia
出处
期刊:Practical radiation oncology [Elsevier]
卷期号:13 (3): e246-e253 被引量:5
标识
DOI:10.1016/j.prro.2022.12.002
摘要

The objective of this study was to evaluate the incidence of brachial plexus injury (BPI) after single-fraction stereotactic body radiation therapy (SBRT) to apical lung tumors.A retrospective cohort analysis was performed of all patients treated with single-fraction lung SBRT at our institution from 2007 to 2022. Apical tumors were identified as those with an epicenter located above the arch of the aorta. Dosimetric analysis of dose to the brachial plexus (BP) was done using both the subclavian vessel (SCV) surrogate structure and anatomic BP. BPI was assessed per Common Terminology Criteria for Adverse Events, version 4.0, as regional paresthesia, marked discomfort and muscle weakness, and limited movement of the arm or hand.A total of 45 patients met inclusion criteria with median follow-up of 21 months. There were 9 patients who exceeded the BP dose constraint using the SCV or anatomic BP volume. Only 1 patient (2.2%) developed grade 2 BPI, occurring 7 months after SBRT. Dose to the anatomic BP for the affected patient was 26.39 Gy. For the entire cohort, the median SCV and anatomic maximum BP doses were 8.44 and 7.14 Gy, respectively.There is considerable variability in dose delivered to the BP after SBRT to apical lung tumors. BPI after single-fraction SBRT to apical tumors is rare and rates are comparable with those reported with multifraction regimens.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
2秒前
张姣姣完成签到,获得积分10
3秒前
海风完成签到,获得积分10
5秒前
易川完成签到,获得积分10
5秒前
薛妖怪发布了新的文献求助10
5秒前
Leo完成签到 ,获得积分10
5秒前
xiao发布了新的文献求助20
6秒前
yyauthor完成签到,获得积分10
6秒前
大乐完成签到 ,获得积分10
8秒前
8秒前
英俊的铭应助俊逸的草莓采纳,获得10
11秒前
11秒前
优秀傲松完成签到,获得积分10
11秒前
烤鸭完成签到 ,获得积分10
12秒前
13秒前
heiha应助lyoncr采纳,获得10
13秒前
15秒前
李健应助开心的傲安采纳,获得10
16秒前
十三不靠发布了新的文献求助10
16秒前
丫丫发布了新的文献求助10
17秒前
苗儿完成签到,获得积分10
18秒前
nice完成签到,获得积分10
19秒前
20秒前
20秒前
luanzhaohui发布了新的文献求助30
21秒前
易川发布了新的文献求助10
21秒前
单身的科研狗关注了科研通微信公众号
22秒前
23秒前
科研通AI5应助黄金矿工采纳,获得10
23秒前
小马甲应助SH采纳,获得10
24秒前
24秒前
niekyang发布了新的文献求助10
24秒前
24秒前
25秒前
Meng发布了新的文献求助10
25秒前
25秒前
十三不靠完成签到,获得积分10
25秒前
25秒前
yaalan完成签到,获得积分10
28秒前
高分求助中
Comparative Anatomy of the Vertebrates 9th 3000
Continuum Thermodynamics and Material Modelling 3000
Production Logging: Theoretical and Interpretive Elements 2700
Les Mantodea de Guyane Insecta, Polyneoptera 1000
Structural Load Modelling and Combination for Performance and Safety Evaluation 1000
Conference Record, IAS Annual Meeting 1977 820
England and the Discovery of America, 1481-1620 600
热门求助领域 (近24小时)
化学 材料科学 生物 医学 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 量子力学 光电子学 冶金
热门帖子
关注 科研通微信公众号,转发送积分 3571872
求助须知:如何正确求助?哪些是违规求助? 3142287
关于积分的说明 9446687
捐赠科研通 2843683
什么是DOI,文献DOI怎么找? 1562971
邀请新用户注册赠送积分活动 731530
科研通“疑难数据库(出版商)”最低求助积分说明 718557