Efficacy and safety of Shouhui Tongbian Capsules in the treatment of constipation : A systematic review and meta-analysis

Review question / Objective: This study is aimed at systematically evaluating the clinical effect and safety of Shouhui Tongbian Capsules in the treatment of constipation and providing evidencebased references for clinical application.All the studies conducted are RCT studies.Condition being studied: To obtain comprehensive results, we will search three Chinese electronic databases and three English databases (PubMed, EmBase and the Cochrane Library) .The Chinese databases were the China Network Knowledge Infrastructure (CKNI, https://www.cnki.net/),Wan Fang database (WF, https://www.wanfangdata.com.cn/) and Chinese Scientific Journal Database (http://qikan.cqvip.com/).Two reviewers will search and evaluate the literature separately according to our inclusion and exclusion criteria.NoteExpress ( professional software for searching and managing the literature ) will be used to identify and remove duplicate or inappropriate studies.Search keywords are as follows: Shouhui Tongbian Capsules, constipation, dyschezia,