戊型肝炎病毒
甲肝
病毒学
病毒性肝炎
流行病学
戊型肝炎
急性肝炎
人口
病毒
甲型肝炎病毒
肝炎
医学
免疫学
生物
环境卫生
基因型
内科学
基因
生物化学
作者
Edgar D. Copado-Villagrana,Julio Y. Anaya-Covarrubias,Oliver Viera‐Segura,Jorge L. Trujillo‐Ochoa,Arturo Panduro,Alexis José-Ábrego,Sonia Román,Nora A. Fierro
出处
期刊:Viral Immunology
[Mary Ann Liebert]
日期:2021-07-06
卷期号:34 (9): 653-657
被引量:8
标识
DOI:10.1089/vim.2021.0045
摘要
Hepatitis A virus (HAV) and hepatitis E virus (HEV) cause most of the global burden of viral hepatitis. Geographical and seasonal patterns contribute to the epidemiological status of infectious diseases. The extent of these features in the setting of HAV and HEV infections has not been analyzed in detail. This point is important in highly endemic countries of both viruses, where the pediatric population is at high risk of contracting these infections. A comparison between the frequency of antibodies to HAV and HEV and viral RNA detection in serum samples from pediatric patients with acute hepatitis from South and West Mexico was performed. All samples were positive for HAV mono-infection, which was most frequently detected in the metropolitan areas during the rainy season in the South (90%) and all year round in the West (42%). No HEV mono-infection was detected in the studied regions. A 58% frequency for HAV/HEV co-infection was found in the West, predominantly in the metropolitan areas during the rainy months. A 10% frequency for co-infection broadly distributed in the South throughout the year was also found. Our findings underscore that the distribution of HAV and HEV infections varies through the year and differs among Mexico's distinct geographical regions.
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