Antithrombotic therapy for cervical arterial dissection

What is the best antithrombotic therapy for cervical arterial dissection? Early anticoagulation was initially the preferred treatment for this condition, but observational studies of treatments for cervical artery dissection have produced mixed results and had inherent biases, 1 Georgiadis D Arnold M von Buedingen HC et al. Aspirin vs anticoagulation in carotid artery dissection: a study of 298 patients. Neurology. 2009; 72: 1810-1815 Crossref PubMed Scopus (116) Google Scholar , 2 Touzé E Gauvrit J-Y Moulin T Meder J-F Bracard S Mas J-L Risk of stroke and recurrent dissection after a cervical artery dissection: a multicenter study. Neurology. 2003; 61: 1347-1351 Crossref PubMed Scopus (212) Google Scholar , 3 Weimar C Kraywinkel K Hagemeister C et al. Recurrent stroke after cervical artery dissection. J Neurol Neurosurg Psychiatry. 2010; 81: 869-873 Crossref PubMed Scopus (34) Google Scholar , 4 Lyrer P Engelter S Antithrombotic drugs for carotid artery dissection. Cochrane Database Syst Rev. 2010; 10CD000255 PubMed Google Scholar leading to uncertainty and a need for randomised trials. Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trialOur findings did not show that aspirin was non-inferior to vitamin K antagonists in the treatment of cervical artery dissection. Full-Text PDF