铜蓝蛋白
肌萎缩侧索硬化
内科学
医学
中枢神经系统
内分泌学
血清
疾病
作者
T I Mzhel'skaia,И. А. Завалишин,И.А. Иванова-Смоленская,E G Larskiĭ,V V Basevich,Elena D. Markova,A S Niiazbekova
出处
期刊:PubMed
日期:1989-01-01
卷期号: (11): 12-6
被引量:2
摘要
Ceruloplasmin (CP) preparations have been used as the reference agents in transition of this protein oxidase activity to blood serum concentrations; the mean concentrations of serum CP varied from 175 to 310 mg/l, depending on the biochemical characteristics of the preparations. Adjustment by the blood serum copper level has proved adequate for clinical studies. CP activity has been found increased in some patients with disseminated sclerosis and lateral amyotrophic sclerosis. CP activity grows with age in normal subjects and in the patients with hereditary extrapyramidal and cerebellar diseases and phenocopies thereof (except hepatocerebral dystrophy). CP activity is higher in women than in men.
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