The Study on Antineoplastic Effective Part of the Stings of Gleditsia sinensis Lam

ObjectiveTo study the separation of anticancer effecive part and antineoplastic function of the stings of Gleditsia sinensis Lam.MethodsAdopt respectively aether precipitator and different polar solvents extraction method to get effective part from total extractive material.The former divides extractive material into lipoclastic and saponin,the latter gets chloroform extract,n-butanol extract and water extract.ResultsThe experiment of resisting S_(180) indicates that saponin and n-butanol extract have obvious antineoplastic function.The most antineoplastic rate are 44.62% and 41.75%respectively.Other samples have not evident antineoplasticfunction.ConclusionSaponin and n-butanol extract are anticancer effective part.