Strategies to stabilise dentine-bonded interfaces through remineralising operative approaches – State of The Art

材料科学 胶粘剂 耐久性 复合材料 玻璃离子水门汀 水解降解 胶原纤维 降级(电信) 牙科粘接 生物相容性 粘结强度 聚合物 图层(电子) 牙科 计算机科学 医学 电信 冶金 解剖
作者
Salvatore Sauro,David H. Pashley
出处
期刊:International Journal of Adhesion and Adhesives [Elsevier BV]
卷期号:69: 39-57 被引量:67
标识
DOI:10.1016/j.ijadhadh.2016.03.014
摘要

Dental adhesive systems have improved considerably over the last ten years, although shortcomings such as post-operative sensitivity, premature reductions in bond strength, interface and marginal degradation, and biocompatibility are still considered important issues with such materials. Enzymatic degradation of collagen fibrils within the hybrid layer and hydrolysis of polymers are the major factors thought to destabilise the resin-dentine interface. However, “smart” resin-based materials that can interact therapeutically with dental hard tissues and reduce the degradation of the resin-dentine interface via remineralisation of the mineral-depleted dental hard tissues can improve the durability of resin-dentine bonds. Moreover, as the resin-dentine interfaces produced by contemporary adhesives are characterised by low mechanical properties, therapeutic remineralising bonding approaches may also contribute to strengthening of hybrid layers, producing more gradual gradients of stiffness that prevents localised stress concentrations. This review attempted to bring together a number of seemingly unrelated events, to show how they may contribute to improvements in the durability of resin-dentine bonds. Innovative new approaches to remineralise the resin-dentine interface may protect hybrid layers from different types of degradations over time, and have a therapeutic role in caries prevention. Recent investigations have revealed that the air-abrasion technique performed with bioactive glass 45S5 (BAG) is capable of creating a therapeutic bioactive smear-layer-covered surface for bonding procedures. BAG can react with body fluids, evoking hydroxyapatite (HAP) precipitation and remineralisation of dentine at the bonded interface, especially when used in combination with fluoride-releasing materials such as glass ionomer cements (GIC) and resin-modified glass ionomer cements (RMGIC). The remineralising potential of these therapeutic approaches is potentiated in the presence of a calcium-sequestering agent such as poly(acrylic acid). However, GIC-based materials as well as calcium silicate cements are not able to restore the mechanical properties of dentine. Thus, experimental adhesive systems containing (30–50 wt%) ion-releasing fillers with advanced remineralising properties and matrix metallo-proteinases (MMP) inhibitors have been developed and used in combination with resin primers containing Ca-sequestering polyanion acids such as poly(aspartic acid) (PASA) or poly(acrylic acid) (PAA) and biomimetic analogues of collagen phosphoproteins such as sodium trimetaphosphate to remineralise resin-dentine interfaces. This biomimetic approach is able to evoke a “bottom-up” remineralisation that restores the original stiffness (i.e. Young׳s Modulus) of water-rich/resin-poor dentine-bonded interfaces. The next step will be the commercialisation of resin-based materials such as flowable composites and “smart” adhesive systems containing biomimetic reagents that can remineralise and prevent degradation of resin-dentine bonds to enhance their clinical longevity.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
岑晓冰完成签到 ,获得积分10
刚刚
啦啦啦完成签到,获得积分10
刚刚
感动的小鸽子完成签到 ,获得积分10
1秒前
lxj完成签到 ,获得积分10
1秒前
无辜的蜗牛完成签到 ,获得积分10
1秒前
xiaojin完成签到,获得积分10
2秒前
程程完成签到,获得积分10
2秒前
duckspy发布了新的文献求助30
2秒前
2秒前
sunyanghu369发布了新的文献求助30
7秒前
hdc12138完成签到,获得积分10
8秒前
飞龙在天完成签到,获得积分0
8秒前
狄淇儿完成签到 ,获得积分10
8秒前
吨吨完成签到,获得积分10
9秒前
小芒果完成签到,获得积分0
13秒前
14秒前
杰克李李完成签到,获得积分10
15秒前
pakiorder完成签到,获得积分20
17秒前
无心的雅霜完成签到,获得积分10
17秒前
1122完成签到,获得积分10
18秒前
王磊完成签到,获得积分10
18秒前
顺心醉蝶完成签到 ,获得积分10
18秒前
量子星尘发布了新的文献求助10
18秒前
zhao完成签到 ,获得积分10
19秒前
yuncong323发布了新的文献求助10
19秒前
gfasdjsjdsjd发布了新的文献求助30
21秒前
pan完成签到,获得积分10
21秒前
22秒前
23秒前
魔幻的妖丽完成签到 ,获得积分10
25秒前
王小凡完成签到 ,获得积分10
25秒前
26秒前
开心薯片发布了新的文献求助10
27秒前
ZXW完成签到,获得积分10
28秒前
莉莉发布了新的文献求助10
28秒前
眼睛大的擎苍完成签到,获得积分10
30秒前
xr完成签到,获得积分10
31秒前
ZORO完成签到,获得积分10
31秒前
32秒前
临时演员完成签到,获得积分10
33秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038235
求助须知:如何正确求助?哪些是违规求助? 3575992
关于积分的说明 11374009
捐赠科研通 3305760
什么是DOI,文献DOI怎么找? 1819276
邀请新用户注册赠送积分活动 892662
科研通“疑难数据库(出版商)”最低求助积分说明 815022