医学
吡非尼酮
特发性肺纤维化
任天堂
生活质量(医疗保健)
重症监护医学
社会心理的
间质性肺病
焦虑
寻常性间质性肺炎
临床试验
心理干预
疾病
内科学
肺
精神科
护理部
作者
Κατερίνα Αντωνίου,Apostolos Kamekis,Emmanouil K. Symvoulakis,Maria Kokosi,Jeffrey J. Swigris
出处
期刊:Current Opinion in Pulmonary Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:2020-07-21
卷期号:26 (5): 457-463
被引量:11
标识
DOI:10.1097/mcp.0000000000000703
摘要
Purpose of review To present an overview of the impact of idiopathic pulmonary fibrosis (IPF) on patients’ emotional well being and quality of life (QoL). Recent findings IPF is an interstitial lung disease which causes irreversible, progressive lung scarring in a pathological pattern of usual interstitial pneumonia. The incidence of IPF is increasing at a global level, subjecting an increasing number of people to its high morbidity and risk of mortality. Diagnosis is based on a multidisciplinary team approach and the exclusion of other interstitial lung diseases. Two novel antifibrotic treatments, pirfenidone and nintedanib, were recently approved by regulatory agencies around the globe, thus providing many IPF patients with treatment options for the first time. Several other drugs have entered the investigational pipeline, including many in early-phase or late-phase clinical trials. Given the incurable and progressive nature of IPF, even with antifibrotic therapy, depression and anxiety are common among patients; these and burdensome symptoms of breathlessness, cough and fatigue are factors that impact patients’ emotional well being and QoL. In addition to even more effective drugs, there is a need for psychosocial interventions and mental health support strategies focused on improving patients’ QoL so they are better equipped to live with this devastating condition. Summary The current article highlights the effects of IPF on patients’ emotional well being and QoL and offers suggestions for strategies to help patients with IPF live as well as possible in their daily lives.
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